Miss. Gov. Reeves cancels redistricting session, GOP House bid stalls


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Republicans hoping to hold the U.S. House hit a setback Wednesday when Mississippi Gov. Tate Reeves indicated he will not immediately pursue redistricting following a critical Supreme Court ruling, as officials seek to oust the leader of Democrats’ January 6 probe.

Following the Supreme Court’s “Callais” ruling on how race can or cannot factor into redistricting, several Republican-led states have moved to redraw congressional maps, arguing for race-neutral approaches — and officials in Jackson quickly took note.

Mississippi lawmakers were primed to convene a special session next week to redraw state Supreme Court and potentially congressional districts, but Reeves canceled the session Wednesday after the judge who ruled the court district maps inhibited Black candidates was overruled — sparking a now-in-limbo effort to oust entrenched former January 6 Committee chairman Bennie Thompson.

“Understand something, that maybe while it may be in the best interest of some individual politicians in Mississippi to talk about congressional redistricting, what happens in Mississippi doesn’t happen in a vacuum,” Reeves said in a talk-radio spot Wednesday.

MISSISSIPPI GOVERNOR SAYS HE WILL CALL SPECIAL SESSION TO REDRAW DISTRICT MAPS AFTER SCOTUS RULING

“I’m going to do what’s in the best interest of Mississippi and I’m going to do what’s in the best interest of America and I’m going work very closely with the Trump administration to accomplish both of those goals.”

Tate Reeves in Mississippi

Mississippi Gov. Tate Reeves speaks after defeating Elvis Presley’s cousin Brandon in the gubernatorial race. (Brandon Bell/Getty Images)

Reeves pushed back on claims he flip-flopped on congressional redistricting, noting the Magnolia State’s March 10 primary has passed — complicating any change in voting landscape, and also said he was onboard with ending what he called Thompson’s 33-year “reign of terror.”

However, Reeves suggested it is not a setback to State Auditor Shad White and others’ renewed bid to shift the Magnolia State’s GOP representation from 3-1 to 4-0 and oust Thompson.

Thompson, a firebrand Democrat from Hinds County seeking his 18th term representing the predominantly Black and largely impoverished Delta region, is in danger of losing his reliably blue seat when redistricting commences.

Thompson and Reeves briefly sparred on X, with the Democrat depicting an elephant painting Mississippi “white” while Reeves countered that Thompson was wrong to claim ownership of the district with the term “my” versus the people of Mississippi.

It must be done to go into effect before the 2026 elections,” replied voting rights activist Scott Presler, while Pastor William Pierce of Columbia drew a state map that comprised evenly divided 22-24-point Republican districts saying “this must be done now” -— as Reeves said the issue is not “if” but “when” and that he plans for the changes to take effect for the 2027 statewide elections.

SUPREME COURT RULES ON KEY VOTING RIGHTS ACT RULE AS REPUBLICANS AND DEMOCRATS WAGE REDISTRICTING WAR

White told Fox News Digital he was the first statewide official to publicly consider drawing-out Thompson and creating a 4-0 map, while Reeves rejected claims of pressure from the White House and Republican Party to redraw now.

As the Supreme Court was set to hand down the Callais ruling, Reeves took to Instagram to say he “do[es]n’t typically make news on a Friday afternoon” but made an “exception” to call a special session 21 days after the decision to consider redistricting.

White, a rising star in the GOP following his major anti-fraud and waste investigations, said that Thompson is “the worst congressman in America” and the state’s map favoring him must be dealt with promptly.

“Among Mississippians; normal taxpayers, Bennie Thompson is incredibly unpopular,” White said in an exclusive Fox News Digital interview Wednesday.

“As chair of the January 6 Committee, anyone who supports President Trump is not happy that Bennie Thompson represents a part of our state.”

TRUMP URGES REPUBLICANS TO ‘BE BOLD’ AS RED STATES PUSH TO REWRITE CONGRESSIONAL MAPS

“[I]t is absolutely both legally and practically possible to change our districts to a 4-0 state,” he said, pointing to Callais and Alabama’s successful bid Monday to get their “Livingston Map” through the courts.

Like Alabama, White said Mississippi officials have “dozens” of already prepared maps to choose from, including some that give each of the four congressional districts an even-keeled level of Trump support totaling 15 points or higher, citing 2024 election results.

“The real question is just whether our politicians here have the courage to actually get Bennie Thompson out. And that question remains unanswered right now,” he said.

White said Mississippi has been stuck with maps featuring a Thompson stronghold for decades, as Thompson himself told Jackson’s NBC affiliate it has been Republicans who have drawn the maps since his 1992 election to Congress.

Thompson said that the issue between the lines in the plans is race.

“I have a voting record that no other person in the [Mississippi] delegation can touch for those things that we need the most: Health care, housing, better educational opportunities… but they’d rather put somebody in position who’s against those things. And the only difference between Bennie Thompson and the rest of the delegation that represent Mississippi in Washington is that I’m Black,” Thompson told Memphis’ NBC affiliate.

REPUBLICAN RIFT PUTS SPOTLIGHT ON HIGH-STAKES SHOWDOWN OVER TRUMP-DRIVEN RED STATE REDISTRICTING

Rep. Bennie Thompson and Rep. Liz Cheney seated at a committee meeting in Washington, D.C.

Rep. Bennie Thompson, chairman of the Select Committee to Investigate the January 6th Attack on the U.S. Capitol, and Vice Chairwoman Rep. Liz Cheney participate in the committee’s last public meeting in the Cannon House Office Building on Capitol Hill in Washington, D.C., on Dec. 19, 2022. (Anna Moneymaker/Getty Images)

Thompson added Mississippi has a history of requiring federal intervention to provide equal rights to Black people, including during the Civil Rights era and suffrage fights, and compared it to the dynamic today, calling it “Jim Crow 2.0” that he will “fight back with every fiber.”

Fox News Digital reached out to Thompson for further comment.

After Reeves’ comments were reported, White told Fox News Digital that he still hopes “Thompson is redistricted-out as soon as possible – even if it’s not going to happen next week.”

Fox News Digital also reached out to Mississippi House Speaker Jason White, R-West, and Senate Leader Dean Kirby, R-Brandon for their take on Reeves’ latest move and efforts to redraw the map.

Meanwhile, Shad White pointed to New England as precedent for Mississippi drawing out Thompson, saying Kamala Harris’ 38% performance mirrors the GOP partisan makeup of multi-district blue states like Connecticut, Massachusetts, Rhode Island, New Hampshire and Maine.

State Sen. Michael McLendon, R-Hernando, joined Shad White’s call to redraw the map to “give Speaker Johnson another ‘+1’ and send Bennie Thompson home.”

ALABAMA REPUBLICANS PLOW FORWARD AFTER KEY SUPREME COURT WIN PUTS CONGRESSIONAL MAP IN QUESTION

He disputed timeframe concerns, saying that Democrats successfully sued Mississippi to redraw his region, costing the GOP their supermajority — and he was still able to run in a mid-off-year primary.

“When Democrats demanded redistricting, the establishment’s response was simple: ‘We have a court order, and we’re going to comply,’” McLendon said in a statement obtained by Fox News Digital. “Now, suddenly, many of those same voices have gone completely silent.”

Asked for his view on the matter, U.S. Rep. Mike Ezell, a Republican from Pascagoula, told Fox News Digital that redistricting is handled by the legislature in Jackson and that he trusts leaders there to “follow the law and do what’s best” for the state.

“My focus remains on serving the people of South Mississippi and fighting for our conservative values in Congress,” Ezell said.

Senate Minority Leader Derrick Simmons, D-Greenville and House Minority Leader Robert Johnson III did not respond to requests for comment.

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With hopes of a 4-0 Mississippi map before the midterms dashed, House Speaker Mike Johnson in neighboring Louisiana will have one fewer likely pickup as he battles a series of Republican retirements and independent voter malaise toward Trump in the effort to keep the House red.

Fox News reached out to the White House for comment.



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Claude reunites stoner with Bitcoin after losing password

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Offbeat

AI to the rescue as 11-year search for password turns up in old PC files

Eleven years ago, a stoner bought some Bitcoin, lit up, and entered a password that he soon forgot. Now, after searching for more than a decade, Claude AI has helped him figure out the credentials he needed to gain access to a crypto wallet containing currency that is now worth a whopping $400,000.

The man, who retains an anonymous online profile only going by the alias “cprkrn,” vowed to name his progeny after Anthropic’s CEO Dario Amodei, all because the AI tool helped him regain access to an Obama-era wallet he thought was impenetrable.

Armed only with an old mnemonic phrase, the man plugged it into Claude and told the AI to search his computer for ways he could use it to figure out the password that could regain access to the 5 Bitcoins he bought in 2015 at a Starbucks.

He told web show MTSlive that he had two of the three passwords needed to open up the wallet, but couldn’t find the crucial third after changing it, and naturally later forgetting it, while he was high.

He said he bought the tokens when the price for each was around $250. Altogether, his Bitcoin stash is now worth just shy of $400,000.

After eight weeks working to crack the password, and after the man gave it access to his old computer used for college work, Claude found a wallet backup that the mnemonic phrase was able to decrypt.

According to an overview of the mission, written by Claude, accessing the wallet backup gave the man access to the private keys required to access the Blockchain.com wallet.

Looking at the wallet’s transaction history shows the funds lying dormant since April 2015, and then being transferred out on Wednesday.

Previous attempts to regain access to the wallet involved brute forcing password strings, 3.5 trillion of them by Claude’s reckoning, all to no avail.

He even traveled back to his parents’ house to retrieve college notebooks, manually entering “anything that looked like password or a seed phrase” he thought might help the AI crack or find the third password.

The man ran Claude for eight weeks to realise he changed the password 11 years ago, while stoned, to “lol420fuckthePOLICE!*:)”.

This is a stellar case study to highlight the value of complex passwords, if there ever was one. ®



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Anatomy of a speech: how does a Republican leader say no to Trump? | US politics

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How does a Republican leader say no to Donald Trump? How do they criticize the US president’s policies without facing a social media riot, or losing their career?

As the party scrambles to redraw key congressional districts after the supreme court effectively gutted a major section of the Voting Rights Act that prevented racial discrimination, all eyes turned this week to South Carolina.

But in a 45-minute address to the state’s senate, Republican majority leader Shane Massey rejected Trump’s demands to redraw its congressional map.

Laying out his case, Massey made clear on Tuesday that he was addressing three audiences: his colleagues in chamber, Republican voters in his state, and the president himself. Democrats – whom he described as “crazy” and “hateful” – were not the intended audience.

And in this rancorous political era, dominated by tribal divisions and binary rhetoric, he tried to craft a nuanced position while senior GOP figures, including Henry McMaster, the South Carolina governor, push to redistrict.

Trump frequently demonizes anyone, especially conservatives, who dare oppose his agenda. Massey made that difficult, by trying to show that he remained firmly aligned with most of the president’s political goals. Just not this one.

double quotation markI had never had the privilege of speaking with the president of the United States until last week. And it really was – it was a privilege. I enjoyed the conversation. It was a very good conversation. He gave me more time in a phone call than I could have expected…

The president told me, he said: “Look, I hope you can help us out.” He said: “But I understand you got to do what you’re comfortable with, you got to do what you think is right.”

He said: “But these people” – talking about the Democrats in Washington – he said:“These people are crazy.” “Yes, sir, I agree with you.” He told me: “These people hate me.”

And I think, Mr President, that’s obvious. There’s no question about that. There is a lot of hatred in Washington. There’s a lot of hatred in the world. And he’s certainly the recipient of a lot of that. There’s no question there.

Six of South Carolina’s seven US congressional districts are held by Republicans. The new map under consideration would dismantle the one district currently held by a Democrat: long-serving representative and party heavyweight James Clyburn.

Massey made clear he wanted Republicans to win the race for US Congress in November’s midterm elections. He touted the power of his party at the state level to advance conservative goals, insisting he agreed with Trump’s concerns and had no qualms about “ticking off” Democrats. “That doesn’t bother me,” Massey said. “I do that every day standing right here.”

But then Massey pivoted into a plain-language analysis of what he sees as practical issues with the proposed last-minute redistricting drive in South Carolina: not an ideological problem, but a legal and technical one.

‘Most people … think we’re freaking crazy’

Massey argued that South Carolina was as gerrymandered – by party, not by race – as possible, without creating a vulnerability for Republicans. He carefully framed his argument not to preserve the district of a Black, Democratic congressman, but to preserve the electability of fellow Republicans in districts that would have to absorb Democratic voters.

He also tore into the details of the proposal and how it sundered “communities of interest”: a term that Black voters have often used in legal arguments against redistricting. Here, Massey turns it on its side to apply it to ruby-red counties, along South Carolina’s coast and elsewhere. By doing so, he highlighted a partisan interest in preserving the local relationships in parts of South Carolina that people in Washington couldn’t identify on an unmarked map, relationships that remain invisible even on a marked map.

Those who drafted the redistricting proposal failed to consider the concerns of “South Carolina and South Carolinians”, Massey suggested. “When they were drawing this map, they didn’t consider those things,” he said.

“They”, in this case, is a faceless other – allowing Massey to avoid laying blame on the president, or on his party’s representatives, by framing the problem as “Washington”, both as an idea and a target.

Even as he was conciliatory toward Trump, cheering the prospect of Republicans retaining the House, Massey expressed contempt for the political product Washington sends back to South Carolina. The broad voting public is increasingly fed up with politics, regardless of party.

“What I am concerned about is how will this be received by people in the middle,” he said of the redistricting drive. “Look, everybody – I think we get lost on this sometimes – everybody in South Carolina is not a rabid partisan like I am. Everybody in South Carolina is not a rabid partisan like we are. Most people in South Carolina think we’re freaking crazy.”

He was less than positive, at times, about his own party’s recent record in US Congress, where it currently has majorities in both the House of Representatives and Senate.

double quotation markI would hope that the home team can retain the majority. And I would also hope that if the home team retains the majority, that they’ll actually do something productive with it. Over the last year and a half, I suspect if we look back at what they’ve done with the majority, I don’t know that anybody in here could name more than one piece of legislation they’ve passed.

And no matter how big and beautiful it was, there’s a whole lot more that they’ve left on the table. And that, to me, is disappointing – to have a majority that doesn’t do anything with it.

The map under consideration is against Republican interests, Massey suggested, even if the party’s leaders in Washington do not know that themselves – calling into question whether it would ultimately leave the party with more, or less, congressional representatives from South Carolina.

‘It is up to us’

A backlash is likely to energize Black voters, which may cost Republicans some seats, he said.

double quotation markTrying to go to 7-0 I think is extremely risky from a political standpoint. I think at best you’re going to get 6-1 and you may even go 5-2. I’ve told the press a number of times, I think if you get cute with this, you could end up in a 5-2 scenario. I don’t want to go 5-2.

I don’t want [Democratic House minority leader] Hakeem Jeffries as the speaker of the House. I think the best chance that South Carolina has to prevent that from happening is with our current maps.

“If the Democrats do win control of the United States House of Representatives, it will not be because of South Carolina,” he said. The unspoken implication: if Democrats win, it will be because of actions taken in Washington DC.

Peppered through the address were references to South Carolina’s independence from Washington, as Massey expressed stark fears about relinquishing it.

double quotation markI cannot in good conscience surrender this authority that has been preserved to, for, and by the states, and merely take orders from those who are not in South Carolina …

I absolutely understand what the president’s concern is here. I understand what the president’s issue is here. I don’t disagree with that. But there are other concerns that we have to consider. Those concerns have not been considered at all with the proposal that we have. Those concerns affect South Carolina and South Carolinians. And it is up to us to consider those things.

If we don’t consider those concerns of South Carolina, there is no one left. We are the last line. I have too much southern blood in me to surrender.

John C Calhoun was an avidly pro-slavery South Carolina senator in antebellum America who argued passionately that states had a right to ignore federal laws they believed were unconstitutional.

Massey reached up to Calhoun’s portrait as he laid out his opposition to a proposal designed to rid South Carolina of its only Black congressman, in an audacious flourish that would have been immediately recognized by his peers.

It is not a reference a Black senator, or a Democrat, is likely to make. It is a reference offered to an audience of white southern conservatives. Massey framed his opposition as upholding the southern tradition of states rights: exactly how white southern conservatives framed their opposition to the civil rights movement.

“I don’t want to be a participant in further eroding federalism, in further diminishing the essential role of states,” he argued. “The states are not mere political subdivisions of the federal government. The states are not here to take orders and direction – the states are sovereign, independent creatures.”

‘Everybody knows it’

Massey addressed the pressure he faced to bow to Trump’s demands, which would have been high on the mind of a Republican lawmaker who saw what happened just last week to Republicans who refused redistricting in Indiana, five of whom lost primary elections to Trump-endorsed candidates.

“There are likely consequences for me, personally, taking the position that I am right now,” he acknowledged. “I’m comfortable with that. I may not like it, but I’m comfortable with it.”

“Too many people in power want to do whatever it takes to stay in power,” said Massey. “I believe the legitimate use of power in this case is to make people safer.”

South Carolina’s senate Republican majority leader pointed to other portraits, as well: James Byrnes, a congressman and US supreme court justice, and Floyd Spence, a congressman who served for 14 terms and chaired the armed services committee.

At the heart of his case was one simple argument – that Washington DC should be listening to South Carolina, not the other way around.

double quotation markWe’ve been able to punch above our weight regardless of the administration, regardless of who the president is, regardless of who occupies the White House. South Carolina has been able to deliver not just for South Carolina, but for the country and the world.

We have had that influence. Doing this will absolutely diminish that influence. It just will. And everybody knows it. Everybody in here, everybody who’s familiar with the process, we understand what’s going to happen here …

Y’all, regardless of who the president is, regardless of who’s in charge, there has to be somebody in South Carolina who can make a phone call and somebody at the White House will answer it. If we don’t have that, South Carolinians are the ones that are going to suffer because of it.

The consequences of this defiance remain to be seen.



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Trump arrives in Beijing with a strong hand against Xi Jinping in talks


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President Donald Trump arrives in Beijing with a strong hand to play in talks with China’s President Xi Jinping. It’s all due to his military and trade moves over the past 16 months.

Of course, to read the press, you’d think doom awaits. “Xi is confident in his country’s power; Trump is weakened with U.S. mired in war,” fretted The Washington Post on Monday, May 11. From New York, the Council on Foreign Relations asserted on Sunday that at the Trump-Xi summit, China will have the upper hand. The general take is that Trump is reeling from the Iran war, while Xi is some sort of mastermind, ready to hop into global leadership. “Xi wants to project China as a more reliable and responsible counterweight to U.S. volatility,” as the Post put it.

You’ve got to be kidding me. The reality is that Trump has put America in a much stronger geopolitical position versus China. Last spring, China was yanking export licenses for critical minerals and jeopardizing factory production around the globe. Now, the U.S. Navy sits athwart China’s No. 1 oil route in the Strait of Hormuz. That’s a new poker hand.

Xi has spent the past year purging military officers, dealing with a slowing economy, and coping with China’s lag in the AI race by turning inward.

TRUMP HEADS TO CHINA WITH THE UPPER HAND — AND XI KNOWS IT

Trump and Xi Jinping shake hands after meeting in South Korea.

Trump is expected to press Xi on China’s economic and strategic support for both Iran and Russia, including oil revenue, dual-use components and potential weapons transfers, according to senior administration officials. (Andrew Caballero-Reynolds/AFP via Getty Images)

In contrast, Trump has cut trade deals around the world attracting trillions of dollars in foreign investment. He’s clobbered Iran’s military and ended the rule of Chinese chum Nicolas Maduro in Venezuela. The U.S. Pacific Fleet has intercepted illicit shadow tankers bound for China’s teapot refineries that sneak in oil from Iran and Russia. The sophisticated display of military power in Operation Epic Fury made eyeballs pop in China’s People’s Liberation Army.

China experts caution Trump is forfeiting prestige by meeting on Xi’s home turf. But for Trump, it’s irresistible. Accompanying Trump to Beijing is an American dream team of CEOs who dominate everything from low Earth orbit (that’s Elon Musk of Tesla and SpaceX) to top-grade aircraft engines (that’s Larry Culp of GE Aerospace.)

He wants to look Xi Jinping in the eye, and there is no substitute for sitting down at a negotiating table.

MARTIN GURRI: LET’S LOOK AT ALL THE GLOBAL BENEFITS TRUMP REAPED BY GRABBING MADURO

Watch for four major moves in Beijing.

Trade

This is a business trip. Team Trump hates what China’s rise did to the USA. Here’s the good news. “Our trade deficit in goods with China fell to $202 billion in 2025—the lowest it has been since 2004. And China’s share of total U.S. imports fell to about 9 percent, the lowest it has been since China joined the World Trade Organization (WTO) in 2001,” U.S. Trade Representative Jamieson Greer testified Apr. 28.

LIZ PEEK: TRUMP’S MAJOR TRADE WINS COULD BE ROCKET FUEL TO US ECONOMY

What Trump wants now is a stable, balanced and civil relationship with China. His plan is managed trade: a new policy where the U.S. and China negotiate tariffs sector by sector and expand trade on non-sensitive goods.

Export deals

Agriculture is at the top of the list, including exports of soybeans, dairy, and corn. Farmers are hoping for a long-term deal with China – although China has failed to live up to similar promises in the past. Aviation watchers predict Boeing could sell China up to 500 airliners and CEO Kelly Ortberg will be on the trip. This is all part of Trump’s plan to narrow the trade deficit. Trump wants America positioned for maximum sales.

TAIWAN WATCHES TRUMP-XI MEETING FOR SIGNS CHINA WILL TEST US RESOLVE

Iran

Trump will come down hard on China for selling Iran sodium perchlorate and other chemicals for ballistic missile fuels. Beijing is already anxious. Secretary of State Marco Rubio just slapped sanctions on Chinese satellite imagery companies and on Qingdao Haiye Oil Terminal Co., which receives Iranian oil. Dwindling oil could hit plastics and chemicals industries and stunt Chinese economic growth.

China experts caution Trump is forfeiting prestige by meeting on Xi’s home turf. But for Trump, it’s irresistible. 

CLICK HERE FOR MORE FOX NEWS OPINION

Artificial Intelligence

Trump and Xi may chit-chat about AI safety, but the U.S. should steer clear of so-called agreements. The U.S. must win the AI race. As of May 1, 2026, the U.S. government’s National Institute of Standards reports the best U.S. model, Open AI GPT 5.5, is approximately eight months ahead of China’s DeepSeek V4 Pro.

CLICK HERE TO DOWNLOAD THE FOX NEWS APP

Whatever you think about AI, you don’t want a world where Xi Jinping sets AI standards. America’s best chance here is the unfettered success of our tech titans and start-ups. They are winning this race with model innovation, and by deploying the whole AI tech stack across global markets ahead of China. Only our U.S. tech sector has the money to compete with China.

China remains a formidable military competitor. China is once again landfilling for new bases in the South China Sea. China has doubled its nuclear missile arsenal from about 250 to over 600 weapons and massive expansion continues unabated. However, Trump’s blend of trade deals and military deterrence is proof positive of America’s unrivaled global leadership.

CLICK HERE TO READ MORE FROM REBECCA GRANT



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Latvian prime minister resigns after drone incident | News

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Latvian Prime Minister Evika Silina has announced her resignation after domestic tension over a Ukrainian drone incident

Latvian centre-right Prime Minister Evika Silina has announced her resignation, after the Progressives Party, her left-leaning coalition partner, pulled support from the government and left her without a majority.

“I ⁠am resigning, but I am not giving up,” Silina, who has been prime minister since 2023, said in a televised statement on Thursday.

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Her resignation came days after Latvia’s Defence Minister Andris Spruds, from the Progressives Party, was forced to resign over the government’s handling of several incidents involving stray drones suspected to be from Ukraine crossing into Latvian territory. Silina said at the time that Spruds had lost her trust and that of the public.

The drone incidents “clearly demonstrated that the political leadership of the defence sector has failed to fulfil its promise of safe skies over our country”, Silina said on Sunday, explaining Spruds’s resignation.

On May 7, two suspected Ukrainian drones entered Latvia, one of them crashing at a fuel storage facility. Multiple Ukrainian drones headed for Russia have hit Baltic countries since March, as well as several other European countries since the Ukraine war started. The incidents have led to domestic criticism of Baltic nations’ abilities to respond to military threats.

Silina’s resignation comes just months before general elections due in October. Latvian President Edgars Rinkevics, tasked with appointing a new head of government, is set to meet with representatives of parliamentary parties on Friday.

“My priority has always been, and remains, the well-being and security of Latvia’s people,” Silina wrote on X on Thursday. “Parties and coalitions change, but Latvia endures. And my responsibility to society comes above all else.”

Ukraine’s Foreign Minister Andrii Sybiha offered to help the Baltic states and Finland to prevent such incidents in the future. He said on Sunday the incidents in Latvia were “the result of Russian electronic warfare deliberately diverting Ukrainian drones from their targets in Russia”



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RenovoRx targets pancreatic cancer with direct chemo delivery system


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Chemotherapy can save lives, but anyone who has watched a loved one go through it knows how hard it can be. The nausea. The exhaustion. The infections. The days when even getting off the couch feels like too much.

That happens because standard chemotherapy travels through the bloodstream. It attacks cancer cells but can also harm healthy cells along the way. For some pancreatic cancer patients, that approach may be changing.

A targeted drug-delivery system from RenovoRx is designed to send chemotherapy directly near the tumor instead of through the entire body. The system, called Trans-Arterial Micro-Perfusion, or TAMP, is being studied in a Phase III clinical trial for locally advanced pancreatic cancer.

For 83-year-old Hernando Salcedo, who had been left weak, nauseous and overwhelmed by standard chemotherapy, the trial offered something he desperately needed: a reason to hope. He enrolled at Miami Cancer Institute and soon began to feel the shift in his own body. His appetite started coming back. His energy improved. He felt more like himself. “The difference was tremendous,” Hernando said. “I completed eight sessions, one every 15 days, and I felt dramatically better than I did with the original chemotherapy.”

HIDDEN FACTOR IN CANCER TREATMENT TIMING MAY AFFECT SURVIVAL, RESEARCHERS SAY

Hernando Salcedo with family at a wedding.

Cancer patient Hernando Salcedo attended a family wedding after RenovoRx’s Trans-Arterial Micro-Perfusion system delivered chemotherapy directly near his tumor, helping him feel stronger during treatment. (Hernando Salcedo)

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How the RenovoRx drug-delivery device works

RenovoRx’s platform uses the FDA-cleared RenovoCath device to deliver chemotherapy through a catheter placed in an artery near the tumor. A physician guides the catheter into position using X-ray imaging.

Shaun Bagai, CEO of RenovoRx, said the platform is designed to localize chemotherapy delivery near the tumor instead of relying on the drug to travel through the whole body.

“Once in position, two small balloons on the catheter are inflated, and the system is adjusted to isolate a targeted segment of artery adjacent to a tumor,” Bagai said. “The chemotherapy drug is then infused between the balloons, creating pressure to push the drug across the vessel wall and near the tumor, directly bathing the target tumor.”

That setup allows doctors to focus treatment in a specific area rather than exposing more of the body to chemotherapy. “The procedure itself is minimally invasive and is typically performed in an outpatient setting without the need for patients to be put under general anesthesia,” Bagai said.

For patients already dealing with pain, fatigue and fear, that outpatient approach may feel less overwhelming than a major hospital procedure.

How targeted chemotherapy for pancreatic cancer works

To understand why this approach matters, it helps to start with the problem doctors are trying to solve. Dr. Ripal Gandhi, a vascular interventional radiologist and interventional oncologist at Baptist Health Miami Cardiac & Vascular Institute and Miami Cancer Institute, explained why standard chemotherapy can be so hard on the body.

“With IV chemotherapy, the drug travels through the bloodstream, affecting both cancerous and healthy cells, which can lead to side effects,” Dr. Gandhi said. TAMP takes a more targeted route. A doctor places a catheter in an artery near the tumor, then delivers chemotherapy into that area instead of relying on the drug to circulate throughout the body.

Dr. Gandhi compared it to “a drip irrigation system for individual plants instead of watering an entire lawn.” For patients, that means doctors are trying to focus more of the treatment near the cancer while reducing how much chemotherapy reaches the rest of the body.

Why pancreatic cancer is so difficult to treat

Pancreatic cancer has a reputation for being one of the hardest cancers to fight, partly because the tumor itself can block treatment from working the way doctors want it to.

Dr. Gandhi said that creates a major challenge for standard IV chemotherapy. “Studies have shown that less than 10% of chemotherapy administered intravenously actually reaches tumor cells due to the few blood vessels in the tumor as well as dense fibrous stroma, which serves as a physical barrier in the tumor microenvironment,” Dr. Gandhi said.

That helps explain why targeted delivery could play an important role. TAMP sends the drug closer to the tumor rather than depending on the bloodstream to do all the work.

“This targeted approach via TAMP does not rely on chemotherapy circulating through the body to carry the drug to the tumor via tumor feeder vessels,” Dr. Gandhi said. “Trans-arterial micro-perfusion is a drug-delivery platform that delivers chemotherapy directly near the target tumor where it is needed most.”

NEW CANCER THERAPY HUNTS AND DESTROYS DEADLY TUMORS IN MAJOR BREAKTHROUGH STUDY 

Chase McCann demonstrating cancerous t-cell treatment at Children's National Hospital

Chase McCann, associate director of the cell therapy lab core, demonstrates how cancerous T-cells from a child are used to develop an autoimmune treatment to fight cancer at Children’s National Hospital in Washington, D.C., on Aug. 26, 2025. (Marvin Joseph/The Washington Post/Getty Images)

Patient says targeted chemotherapy gave him hope

Hernando’s cancer journey began after he went to the doctor with a swollen stomach and hip pain. Doctors diagnosed him with locally advanced pancreatic cancer. When he started standard chemotherapy in August 2015, the side effects hit hard. “My body was going through an incredible amount of stress,” Hernando said. “My stomach was inflamed, I had persistent pain in my head, and I had almost no energy.”

He was also receiving chemotherapy and radiation at the same time. “It was a very difficult period, both physically and emotionally,” he said. “I remember feeling exhausted, overwhelmed and unsure of what the future would look like.”

When doctors presented the targeted treatment option, Hernando saw it as more than another medical procedure. “To me, it felt like a new opportunity to live,” he said. “It gave me hope at a time when my family and I really needed it.”

He credits Dr. Gandhi and the team at Miami Cancer Institute with helping him through it all. “From the beginning, he was honest, supportive and clear with my wife, my family and me,” Hernando said. “That meant everything.” 

Fewer chemotherapy side effects changed daily life

“Before, I was losing weight, had no appetite and felt drained,” Hernando said. “After switching treatments, things began to change. I stopped losing weight, my appetite came back, my color improved and I had more energy.”

Cancer treatment can sometimes take over everyday life. When side effects ease, patients can get pieces of their normal life back. “After about eight weeks, we could see real progress,” Hernando said. “I was eating more, moving more and feeling excited about life again.”

One moment still stands out. Hernando was able to attend a family wedding and dance the entire night. “That moment meant everything to me,” he said. “After everything I had been through, being able to celebrate with my family in that way felt like a gift.” For Hernando, it was a chance to feel like himself again. “That night at the wedding, I was not thinking only about cancer or treatment,” Hernando said. “I was living.”

Early trial results show survival and quality-of-life signals

The early data from RenovoRx’s Phase III TIGeR-PaC trial suggest the targeted approach may offer both survival and tolerability benefits for some patients.

Dr. Gandhi said completed clinical studies with TAMP in pancreatic cancer showed “a potential for better outcomes and less side effects for patients.”

“In the initial interim analysis of the TIGeR-PaC clinical trial, there was a trend towards improved overall survival by 6 months and improvement in the progression free survival by 8.1 months with 65% fewer adverse events in the TAMP arm of the study,” Dr. Gandhi said.

Who may benefit from targeted chemotherapy delivery?

This approach isn’t for every pancreatic cancer patient. Doctors still need to look at the cancer stage, tumor location, treatment history and whether the cancer has spread.

Dr. Gandhi said Hernando was the kind of patient who could be a strong fit. “He is precisely the type of patient who would benefit best from this approach because he has a tumor which is too far advanced to be treated surgically, but it has not spread to other organs,” Dr. Gandhi said.

He also pointed to clinical trials as an important option for pancreatic cancer patients.”I discussed with him that the recommendation of the National Comprehensive Cancer Network is that the best management for pancreatic cancer patients is participation in a clinical trial whenever possible and he was an ideal candidate,” Dr. Gandhi said.

He went on to say that TAMP may be an option for patients who are not candidates for surgery, patients who have failed chemotherapy or patients who no longer want to continue IV chemotherapy because of side effects.

“TAMP can be used at any point within the treatment landscape, before, during or after other treatment modalities such as IV chemotherapy or radiation,” he said.

PANCREATIC CANCER PATIENT SURVIVAL DOUBLED WITH HIGH DOSE OF COMMON VITAMIN, STUDY FINDS

The RenovoCath device is shown.

The RenovoCath device uses a catheter-based system to deliver chemotherapy near the tumor instead of through the whole body. (RenovoRx)

What comes next for RenovoRx’s cancer treatment platform

RenovoRx says the RenovoCath catheter is already FDA-cleared for general therapy and chemotherapy delivery. The company is also nearing the end of enrollment in its Phase III TIGeR-PaC trial.

That trial is evaluating intra-arterial gemcitabine (IAG) delivered through RenovoCath for locally advanced pancreatic cancer. Bagai said enrollment is expected to be completed in mid-2026, with final results expected in 2027.

“If positive, data generated from this trial could potentially support a new drug application for this combination product to the FDA for IAG,” Bagai said. RenovoRx also sees potential beyond pancreatic cancer. “The challenge we are addressing is not unique to pancreatic cancer,” Bagai said.

He said the platform could apply to other solid tumors with limited blood supply, including bile duct cancer, certain lung cancers and sarcomas. “The platform is designed to work with different types of therapies, not just one drug,” Bagai said. “That opens the door to future combinations and potential partnerships, with the goal of expanding options for patients who have limited treatment choices.” 

What this means to you

If you or someone you love has pancreatic cancer, this story is worth paying attention to. Clinical trials can open up options when standard treatment feels too hard to tolerate or stops working.

Drug delivery matters, too. The medicine itself is only part of the story. Where it goes inside the body can affect side effects, energy levels and quality of life. Targeted chemotherapy delivery remains a specialized treatment approach. Some cancer centers may not offer it, and every diagnosis will not be a fit. Your care team can review imaging, staging, prior treatments and overall health to see whether it makes sense.

Start with direct questions. Ask whether a clinical trial makes sense. You can also ask about targeted delivery options or a second opinion from a pancreatic cancer specialist. Hernando’s advice to other patients is simple. “I would tell them not to lose hope and not to wait to ask questions,” he said. 

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Kurt’s key takeaways

Pancreatic cancer has a way of turning normal life upside down fast. One day, a family is making plans. The next, they are trying to understand scans, treatment choices and side effects that no one feels ready for. That is what makes Hernando’s story so powerful. The part that stays with you isn’t only the technology. It is the fact that he started eating again. He had more energy. He felt more like himself. And he got to dance at a wedding after wondering what the future would look like. The final Phase III trial results will be important. Doctors still need to see how widely this approach could help patients. But the promise is easy to understand. If chemotherapy can get closer to the tumor while taking less of a toll on the rest of the body, patients may get something that matters just as much as treatment itself: more good days.

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Serie A finish in chaos, worsened by clash with Italian Open tennis final | Football News

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Serie A hit by final weekend chaos multiplied by Italian Open men’s tennis final booked in same venue as Rome derby.

Italian football is facing another embarrassment to add to the country’s failure to qualify for a third consecutive World Cup.

With just three days to go until the start of the penultimate round of Serie A fixtures, Italy’s top-flight league, half the teams do not know when their matches will be played.

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The Rome derby is at the core of the issue as it was originally slated to kick off at 12:30pm (10:30 GMT) on Sunday, along with four other matches involving teams competing for a Champions League berth.

Because the race for the final three Champions League spots – behind newly crowned champion Inter Milan – is so tight, the games featuring Napoli, Juventus, AC Milan, Roma and Como all have to be played simultaneously to ensure fairness.

However, the Italian Open men’s singles tennis final is scheduled for 5pm (15:00 GMT) at Rome’s Foro Italico, in the same complex as the Stadio Olimpico and, because of fears of public safety, local authorities have ordered the derby to be moved to Monday evening.

Because of the disruption that would cause to thousands of fans of the 10 teams involved, the Lega Serie A proposed an alternative: kicking off at 12pm (10:00 GMT) and pushing back the start of the tennis to 5:30pm (15:30 GMT).

That was rejected by Roman authorities, and so the Italian league’s governing body lodged a formal appeal with the Regional Administrative Tribunal (TAR) on Wednesday night.

Lazio coach Maurizio Sarri was asked about the matter on Wednesday, after his team’s loss to Inter in the Italian Cup final, and he blamed the Lega Serie A, adding that he would not even turn up at the stadium if the derby was played on Sunday.

“We could have thought of this overlap, but at the time, elements such as five matches simultaneously and Lazio’s Italian Cup final were missing,” Lega Serie A President Ezio Simonelli said. “It certainly won’t happen again.

“Out of a sense of responsibility also towards the 300,000 fans involved, we proposed a solution, and I assure you that bringing forward a match by half an hour is not a usual thing. We are asking the players and teams to make a sacrifice.”

Five points separate Napoli, in second, and sixth-place Como. Napoli is on 70 points, Juventus 68, Milan and Roma 67 and Como 65.

They are all playing against teams with little to play for but pride, with Napoli visiting already relegated Pisa, while Juventus, Milan and Como play Fiorentina, Genoa and Parma respectively — with those three sides already safe from relegation.

Lazio is out of the race for the European spots.

At the other end of the table, Lecce – which occupies the last position of safety – is one point above 18th-place Cremonese and visits Sassuolo. Cremonese travels to Udinese.

Italy’s national team became the first former winners to miss out on qualification for three consecutive World Cup finals when they were eliminated by Bosnia and Herzegovina in a playoff on March 31.

The defeat has led to calls for widespread change to the way Italian football is structured and managed, including the Italian sport minister calling for the football federation’s president to stand down.



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